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The GMP manufacturing professionals at Bachem Pharma have over 50 years of cumulative experience in peptide process development, scale-up, and cGMP (Current Good Manufacturing Practice) standards, as defined by the FDA. We manufacture peptides using solution-phase (liquid-phase or LPPS), solid-phase peptide synthesis (SPPS), or hybrid processes.
Pharmaceutical Services: We provide comprehensive pharmaceutical peptide services to support your drug development processes. With advanced technology and expertise in peptide chemistry, we offer services that ensure your peptide-based drugs achieve optimal efficacy, stability, and safety
Our teams have developed, scaled up, and manufactured up to 200 kg of GMP peptide APIs using the solid-phase process, as well as up to 50 kilograms of peptide APIs through convergent solid and solution-phase synthesis processes. We also develop and manufacture custom peptides, New Drug Peptide Entities, Encapsulated peptides, and oral lozenges under current Good Manufacturing Practice (cGMP) conditions
Whether you need a peptide for early research, a new chemical entity (NCE) starting clinical trials or commercial production, or analytical development and validation services, we would be happy to be your partner.
We provide comprehensive services for developing and producing glycosylated peptides, catering to quantities ranging from milligrams to kilograms. Our expertise in glycosylation enhances the bioavailability, stability, and targeting capabilities of peptides, making them highly valuable for various research and therapeutic applications.
Bachem Pharma's peptide drug discovery service addresses key concerns, including immunogenicity, poor pharmacokinetics, lack of oral bioavailability, and high manufacturing costs. Utilizing our proprietary technologies and expertise, we develop peptide drugs that are both effective and commercially viable.
Bachem Pharma manufactures the highest-quality peptides at the lowest costs in the industry. We have established relationships with major raw material manufacturing companies for amino acid derivatives, resins, and solvents, and can pass these savings on to our clients.
Due to the large quantities of raw materials we purchase, we can maintain lower costs than many of our competitors. Additionally, we utilize solvent recovery systems to reduce manufacturing costs on a large scale.
Peptide Drug Bioconjugation: We offer custom bioconjugation strategies, allowing drugs to be combined at the C-terminus, N-terminus, or within the peptide sequence. This service is ideal for creating peptide-based conjugates, providing a fast and efficient solution for developing novel therapeutic agents.
Peptide Lead Optimization: Lead optimization is crucial in developing peptide drugs. Our service involves modifying lead peptides to enhance their pharmacokinetic properties, thereby ensuring improved bioavailability and stability. This process is essential for transforming lead peptides into "drug-like"
compounds that exhibit the desired pharmacological effects.
With fully controlled cGMP systems, rigorous processes, and experienced management, we can offer our partners the most competitive manufacturing costs, whether using solution-phase or solid-phase peptide synthesis..
In addition to producing peptide products under GMP (Good Manufacturing Practice) standards and requirements, we also provide process development and analytical services for research or non-GMP/GLP grade peptides.
These non-GMP peptide services are available for a broad range of customers, including Universities, Research Organizations, Biotechnology Companies, Pharmaceutical Companies, and more. We can accommodate a variety of research scales and offer additional analytical and storage services.
No matter where your project starts, Bachem Pharma is the partner you need for a fully integrated solution, from preclinical to commercial stages. We eliminate the hassle of managing multiple providers by offering:
✔ Faster Time to Market
✔ Guaranteed Regulatory & Quality Standards
✔ Transparent Communication & Full Batch Record Access
✔ Cost-Effective Processes with Green Chemistry Principles
✔ Flexible Response to Changing Needs
✔ Stability Testing Services
✔ Peptides from API to Drug Product
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